University of Bristol and Severn Foundation School
ADULT DIABETES AND ENDOCRINOLOGY
Bristol is a major centre for diabetes and endocrinology with 4 clinical and 6 basic science Professors, major laboratory bases in Southmead and the new Dorothy Hodgkin Building at the UBHT site as well as an expanding portfolio of clinical trials. Interests include the predicting Type 1 diabetes (Professors Gale and Bingley), the immunotherapy of Type 1 diabetes (Drs Dayan and Wong), the neuroendocrinology of stress (Prof Lightman), the endocrinology of exercise (Dr Andrews/ Prof Tavare). Successful candidates would be invited to choose between clinical and laboratory projects over the range of subject areas. Overall mentorship will be provided by Dr Dayan and the AF2 will have a project supervisor depending on their choice of subject area. Along with participation in the core research training curriculum, the 4 months period will provide hands on experience in laboratory work or a major clinical project, as well as outputs including co-authorship of papers, preparation of a review or a poster for a national meeting. In addition, trainees will have the opprotunity to gain exposure to specialist clinical experience in diabetes/endocrinology through exposure to a range of clinics.
Contact: Dr Colin Dayan
colin.dayan@bristol.ac.uk
CLINICAL EPIDEMIOLOGY/PUBLIC HEALTH
Clinical epidemiology is the discipline that determines causes of disease in populations and combined with health services research evaluates diagnostic, prognostic and clinical interventions. The Department of Social Medicine is a leading centre for life course and genetic epidemiology, health services research and public health in the UK and was one of only three to be awarded the top 5* grade in the 2001 Research Assessment Exercise. The 4 month attachment would enable the trainee to learn about specific epidemiological and statistical methods through the hands-on analysis of data that has already been collected, leading to a peer-reviewed publication. The trainee would be supported by a senior clinical academic. There may also be opportunities to observe or help with data collection. Current areas of interest include insulin-like growth factors, insulin resistance syndrome, prostate cancer, multiple sclerosis, sodium composition of infant feeds, early life origins of chronic diseases, Mendelian Randomisation, mental health and neurodegenerative disorders.
Contact: Professor Yoav Ben-Shlomo
y.ben-shlomo@bristol.ac.uk
MEDICAL PHYSIOLOGY
The Department has a strong national and international reputation, and many of its research groups are currently engaged in a variety of trans-disciplinary collaborations with clinical researchers. The successful applicants will be offered a choice of laboratory research projects (supervised by either Professor Paton or Dr Pickering). These have been selected to provide experience of the use of cutting edge bioscience to address current clinical problems (hypertension and chronic pain). This work will be tailored to provide a motivated candidate with a tangible foundation (training in translational basic science combined with a likelihood of presentations to learned societies and publications) from which to launch a career as a clinical academic. In addition the Department will provide opportunities for training and exposure to teaching in areas that will be matched to the research projects (CVS, Pain) and will encourage attendance at our research seminar programmes.
Contact: Dr Tony Pickering
Tel: (0117) 331 7579
Tony.Pickering@bristol.ac.uk
www.bristol.ac.uk/phys-pharm
ADULT RENAL MEDICINE
The post will be based at Southmead Hospital with the academic component in the Academic Renal Unit, University of Bristol. The Academic Renal Unit is headed by Professor Peter Mathieson. Our main research interest is human glomerular cell biology, studying the mechanisms whereby the normal kidney allows very little protein to escape into the urine. The academic F2 will be offered a choice of ongoing projects, provided with full supervision/training and encouraged to present their work to our regular laboratory meetings. There will be an opportunity to attend nephrology teaching sessions locally and regionally as well as any taught courses deemed suitable.
Contact: Professor Peter Mathieson
p.mathieson@bristol.ac.uk
PAEDIATRICS – ENDOCRINE/RENAL
This post will be attached to the renal and endocrine teams based in the purpose built Bristol Royal Hospital for Children, a tertiary referral centre for the South West. Good links with the clinical service will be part of the post, which will offer laboratory based research focusing on primary cell culture in muscle and fat studying insulin resistance and nutrition; unique podocyte cell lines examining many renal glomerular conditions and on the Insulin Like Growth Hormone axis in health and disease.
Contacts: Professor Julian Hamilton Shield and Professor Moin Saleem
j.p.h.shield@bristol.ac.uk
M.Saleem@bristol.ac.uk
PAEDIATRICS – INFECTIOUS DISEASES/MICROBIOLOGY
The trainee will conduct a project within an existing programme of infectious diseases research which focuses on the diagnosis, pathogenesis and immune responses to infections with Streptococcus pneumoniae and Neisseria meningitidis. Projects will be laboratory based but will usually involve analysis of clinical samples from patients. Supervision will normally be jointly between paediatrics and microbiology.
Contact: Professor Adam Finn
Tel: (0117) 342 0174
Adam.Finn@bristol.ac.uk
PAEDIATRICS – CHILD AND ADOLESCENT HEALTH
The Centre for Child and Adolescent Health is a multi-disciplinary academic centre funded by the Universities of Bristol and the West of England, with close links with local NHS partners. Research at the Centre is organised into 4 themes: Nutrition in early childhood, Child development and disability, Children’s palliative care and complex health needs, and Childhood injury. We have a strong interest in international child health, running an intercalated BSc in International Health and maintaining several active research collaborations with overseas partners. The trainee will have a wide range of projects to choose from, including chronic fatigue syndrome, autism, developmental dyslexia, child injury and palliative care for children. Supervision will be provided by a senior clinical academic paediatrician.
Contact: Professor Alan Emond
Tel: (0117) 331 0893
alan.emond@bristol.ac.uk
www.bristol.ac.uk/ccah
PRIMARY HEALTH CARE
Academic primary care is situated in the Department of Community Based Medicine. In the 2008 RAE, 70% of our research was rated either 4* or 3* (of international standing). We have a long and strong track record of supporting medical students on SSCs and electives, and training academic GPs with particular success in supporting academic GP registrars and training fellows. Our current areas of interest include primary care mental health, service delivery, diabetes, complementary and alternative medicine, and cardio-vascular medicine. We use a wide range of research methodologies. You would have a lot of flexibility in choosing your project and be supervised by a senior clinical academic GP.
Contact: Professor Debbie Sharp
Tel: (0117) 3313812
Debbie.sharp@bristol.ac.uk
www.bris.ac.uk/Depts/PrimaryHealthCare
PSYCHIATRY
The Academic Unit of Psychiatry (www.bristol.ac.uk/psychiatry) has two strong research groupings in epidemiology and psychopharmacology. Psychiatric research is now benefiting from the substantial growth in neuroscience over the past 10-15 years and this will have increasing influence over new treatments and understanding of mechanisms: biological, psychological and social. We have a wide range of projects in the Unit including studies involving neuroimaging, experimental medicine designs, randomised controlled trials and large population based studies.
Contacts: Professor Glyn Lewis and Dr John Potokar
Tel: (0117) 954 6796
glyn.lewis@bristol.ac.uk
Tel: (0117) 954 6663
john.potokar@bristol.ac.uk
SURGERY
The academic component of this rotation will be linked to the upper gastrointestinal team at University Hospitals Bristol NHS Foundation Trust and the Department of Social Medicine based at Canynge Hall. The successful applicant will be offered a choice of health services research projects aimed to provide experience of health outcomes research in surgical oncology or minimal access surgery. You will have the opportunity to learn several methodologies and be involved in writing and presenting papers.
Contact: Professor Jane M Blazeby
Tel: (0117) 928 7231
j.m.blazeby@bristol.ac.uk